Author ' s response to reviews Title : miR - 124 a and miR - 137 inhibit
نویسندگان
چکیده
Joachim Silber ([email protected]) Daniel A Lim ([email protected]) Claudia Petritsch ([email protected]) Anders I Persson ([email protected]) Alika K Maunakea ([email protected]) Mamie Yu ([email protected]) Scott R Vandenberg ([email protected]) David G Ginzinger ([email protected]) C David James ([email protected]) Joseph F Costello ([email protected]) Gabriele Bergers ([email protected]) William A Weiss ([email protected]) Arturo Alvarez-Buylla ([email protected]) J Graeme Hodgson ([email protected])
منابع مشابه
Author ' s response to reviews Title : miR - 124 a and miR - 137 inhibit proliferation of GBM cells and induce differentiation of tumor stem cells
Joachim Silber ([email protected]) Daniel A Lim ([email protected]) Claudia Petritsch ([email protected]) Anders I Persson ([email protected]) Alika K Maunakea ([email protected]) Mamie Yu ([email protected]) Scott R Vandenberg ([email protected]) David G Ginzinger ([email protected]) C David James ([email protected]) Joseph F Costello (Joseph.Costello@uc...
متن کاملmiR-124, miR-137 and miR-340 regulate colorectal cancer growth via inhibition of the Warburg effect.
Colorectal cancer represents one of the most challenging diseases. Increasing evidence indicates that aberrant expression of microRNAs (miRNAs) is related to pathogenesis of colorectal cancer. Cancer cells reprogram metabolic pathways to sustain higher proliferation rates. Whether mechanisms underlying the role of miRNA in colorectal cancer are in...
متن کاملXWH - 09 - 1 - 0583 TITLE : Deregulation of miRNAs contributes to development and progression of prostate cancer
Although prostate cancer (CaP) is the most frequently diagnosed malignant tumor in American men, the mechanisms underlying the development and progression of CaP remain largely unknown. Recent studies have shown that downregulation of miR-124 occurs in several types of human cancer, suggesting a tumor suppressive function of miR-124. Until now, however, it has been unclear whether miR-124 is as...
متن کاملThe microRNA miR-124 suppresses seizure activity and regulates CREB1 activity.
miR-124, a brain-specific microRNA, was originally considered as a key regulator in neuronal differentiation and the development of the nervous system. Here we showed that miR-124 expression was suppressed in patients with epilepsy and rats after drug induced-seizures. Intrahippocampal administration of a miR-124 duplex led to alleviated seizure severity and prolonged onset latency in two rat m...
متن کاملAberrant expression of miRNAs predicts recurrence and survival in stage-II colorectal cancer patients from Egypt
Background: Patients with stage II CRC have a varying survival outcome. Therefore, it is critical to identify prognostic biomarkers that can define more aggressive forms of the disease. We assessed the expression levels of five miRNAs that have been previously addressed in relation to the development and progression of solid and hematological tumors. Methods: We measured the expression levels o...
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